Development and validation of stability-indicating UPLC method for the determination of lafutidine and its impurities in bulk and pharmaceutical dosage form

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Development and Validation of a Stability Indicating RP-UPLC Method for Determination of Quetiapine in Pharmaceutical Dosage Form

The present work reports a stability indicating reversed phase ultra performance liquid chromatography (RP-UPLC) method for the quantitative determination of quetiapine in pharmaceutical dosage form. The chromatographic separation is performed on an Agilent Eclipse Plus C18, RRHD 1.8 μm (50 mm x 2.1 mm) column using gradient elution. The optimized mobile phase consists of 0.1 % aqueous triethyl...

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A validated stability-indicating UPLC method for desloratadine and its impurities in pharmaceutical dosage forms.

A novel stability-indicating gradient reverse phase ultra-performance liquid chromatographic (RP-UPLC) method was developed for the determination of purity of desloratadine in presence of its impurities and forced degradation products. The method was developed using Waters Aquity BEH C18 column with mobile phase containing a gradient mixture of solvents A and B. The eluted compounds were monito...

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A New Stability Indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Dolutegravir and Rilpivirine in Bulk and its Dosage Forms

A New Stability Indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Dolutegravir and Rilpivirine in Bulk and its Dosage Forms. Abstract The objective of the work is to develop and validate a new, simple, highly sensitive, stability indicating RP-HPLC method for simultaneous estimation of Dolutegravir and Rilpivirine in bulk and its dosage f...

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Stability Indicating Analytical Method Development and Validation of Lafutidine in Tablet Dosage Form by Rp- Hplc

Objectives: To perform stability indicating analytical method development and validation of Lafutidine in tablet dosage form by reverse phase HPLC method. Materials and Methods: The method was developed employing isocratic RP-HPLC and validated for assay of Lafutidine in tablet dosage form. The method employs the use of a UV detector. Results: The developed assay method was found to be accurate...

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ژورنال

عنوان ژورنال: International Journal of Industrial Chemistry

سال: 2013

ISSN: 2228-5547

DOI: 10.1186/2228-5547-4-32